IN THE NEWS
The Rochester Epidemiology Project has laid the foundation for hundreds of research studies to try and answer questions about health care issues that affect our community. Listed below are some of the news articles discussing the results of recent publications using REP data.
Admissions Up in RA After Heart Failure Dx—Most hospitalizations were for noncardiovascular causes, which carry a high burden
Among adults who developed heart failure, rates of hospitalization for those previously diagnosed with rheumatoid arthritis (RA) were higher than for patients without RA, a retrospective study found.
Article: MEDPAGE TODAY
Scientists discover autoimmune disease associated with testicular cancer
Using advanced technology, scientists at Chan Zuckerberg (CZ) Biohub, Mayo Clinic and University of California, San Francisco (UCSF), have discovered an autoimmune disease that appears to affect men with testicular cancer.
5-year overall survival in patients with lung cancer eligible or ineligible for screening according to US Preventive Services Task Force criteria: a prospective, observational cohort study
The US Preventive Services Task Force (USPSTF) recommends lung cancer screening among individuals aged 55–80 years with a 30 pack-year cigarette smoking history and, if they are former smokers, those who quit within the past 15 years.
Article: The Lancet
Stroke type unrelated to anti-VEGF treatment
The type of stroke suffered, whether ischemic or hemorrhagic, in patients with retinal disease was not influenced by anti-VEGF treatment, according to a study. A retrospective consecutive review of patient records in the Rochester Epidemiology Project from Jan. 1, 2004, through Dec. 31, 2013, identified 690 patients (case cohort) as receiving an intravitreal injection for age-related macular degeneration (AMD), diabetic macular edema (DME), proliferative diabetic retinopathy (PDR) or retinal vein occlusion (RVO).
Mayo Clinic study explores cumulative radiation from CT use
A new population-based study by Mayo Clinic researchers explores how often computed tomography (CT) scans are used in practice, and what that means in terms of total dose of ionizing radiation that people are getting. The new study also describes what clinical indications most commonly led to CT scans, and identifies some interesting disparities. The study available online in Mayo Clinic Proceedings, is based on patient records from the Rochester Epidemiology Project.
Article: Advancing the Science
Study Finds That Disability in RA Begins 1 to 2 Years Before Diagnosis
Functional disabilities start to appear in patients with rheumatoid arthritis (RA) 1 to 2 years before diagnosis, signaling that earlier diagnosis and more aggressive treatment may lessen the burden of disease, according to a study released today.
Article: The Center for Biosimilars
Antiphospholipid syndrome affects 1 in 2,000, peak risk among elderly
Antiphospholipid syndrome has an estimated prevalence of 50 individuals per 100,000 with an annual incidence rate of 2.1 per 100,000, notably higher among patients older than 55 years, according to data published in Arthritis & Rheumatology.
Article: Healio Rheumatology
Anti-VEGF Treatment Not Linked to Increased Risk of Stroke, Myocardial Infarction or Death
Anti-vascular endothelial growth (anti-VEGF) therapy for age-related macular degeneration (AMD) is not linked to the increased risk of stroke, myocardial infarction, or death, according to a new report.
Article: MD Magazine
Antidepressant Overprescribing Appears Common in Elderly
Potential antidepressant overprescribing appears to be common among elderly patients and involves mostly newer antidepressants used for nonspecific psychiatric symptoms and subthreshold diagnoses, according to a study published online Jan. 23 in Pharmacology Research & Perspectives.
Prediction tool for kidney stones
Kidney stones are a common and painful condition, with many sufferers experiencing recurrent episodes. Most people who pass an initial stone want to know their chances of future episodes, but this has not always been easy to predict. Now researchers are tracking the familiar characteristics of kidney stone formers in an online prediction tool that could help sufferers anticipate if they’ll experience future episodes.
New data gives clarity to allergy doctors and their patients
In a new study published in Mayo Clinic Proceedings, Mayo Clinic researchers present the first population-based evidence showing how often food allergies are diagnosed in people. The study also determined which foods are most likely to cause allergic reactions in different age groups.
Article: Advancing the Science
Mayo researchers find ‘unacceptable low’ cervical cancer screening rates
The percentage of women who are screened for cervical cancer may be far lower than national data suggests, according to a Mayo Clinic study recently published in the Journal of Women’s Health. Less than two-thirds of women ages 30 to 65 were up-to-date with cervical cancer screenings in 2016. The percentage is even lower for women ages 21 to 29, with just over half current on screenings. Those figures are well below the 81 percent screening compliance rate self-reported in the 2015 National Health Interview Survey.
EHR Data Helps Predict Survival for Patients With Circulatory Issue
A group of researchers from Mayo Clinic used EHR-integrated risk calculators to predict survival rates for patients with peripheral arterial disease (PAD) using EHR data.
Mortality high in squamous cell carcinoma in hidradenitis suppurativa
Incidence of squamous cell carcinoma in hidradenitis suppurativa is very rare, with fewer than 100 cases in published records. However, the mortality rate is very high, so it must be treated aggressively.
Rethinking lethality in youth suicide attempts
First suicide attempts are more lethal than previously realized, reports a study of children and adolescents published in the Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP).
The rising tide of nonalcoholic fatty liver disease
Liver disease? Me? I don’t drink. I don’t smoke. Okay, so I don’t exercise that much, and where did all these candy bar wrappers come from?Anyway, I thought liver disease was just for alcoholics?These are question many Americans ask when diagnosed with nonalcoholic fatty liver disease. But as its name implies, NAFLD is an umbrella term for a range of liver conditions in people who drink little or no alcohol. In NAFLD, excess fat is stored in the liver, and can lead to inflammation, scarring and potentially liver failure.
Ovary removal may increase risk of chronic kidney disease
Premenopausal women who have their ovaries surgically removed face an increased risk of developing chronic kidney disease, according to a Mayo Clinic study published on Wednesday, Sept. 19, in the Clinical Journal of the American Society of Nephrology.
Probing congenital nasolacrimal obstruction may be OK in 9- to 15-month-olds
The optimal time window to probe the tear duct of a child with congenital nasolacrimal duct obstruction (CNLDO) may be earlier and narrower than previously thought, researchers suggest.
Shedding Light on the ‘Sunshine Vitamin’
Vitamin D, sometimes referred to as the ‘sunshine vitamin,’ comes up frequently in the clinical setting. Over the last few decades, we have learned that vitamin D may actually have a much broader role in human health than once thought. Vitamin D deficiency has been associated with multiple diseases and death. Read about our latest research.
Hospitalization Increases Risk for Acute Gout Flares
The risk for gout flares increases 10-fold during hospitalization and longer hospital stays are linked to in-hospital gout flares, according to a study recently published in The Journal of Rheumatology.
Normal weight with central obesity increases CV risk
Patients who had normal weight and central obesity had an increased CV risk compared with those with normal BMI without central obesity and with those with abnormal BMI without central fat distribution, according to data presented at the American Society for Preventive Cardiology Congress on CVD.
Mayo Clinic study: Anesthesia, surgery linked to decline in memory and thinking
In adults over 70, exposure to general anesthesia and surgery is associated with a subtle decline in memory and thinking skills, according to new Mayo Clinic research.
Pre-eclampsia in pregnancy indicator of hardened arteries in later life
Women who suffer pre-eclampsia when pregnant have a heightened risk of a hardening of the arteries in later life, according to a new study.
Half of patients with posterior shoulder instability were successfully treated nonoperatively at 1 year
Among patients with posterior shoulder instability who had nonoperative management for at least 1 year, 40% of the patients will require surgery within 10 years, according to long-term study results presented here.
Social isolation plus heart failure could increase hospitalizations, deaths
Patients with heart failure who felt socially isolated were much more likely to die or be hospitalized than more socially connected patients, according to new research in Journal of the American Heart Association.
Belly fat: What it really means about your health – even if you’re not overweight
BELLY fat is not just something seen in overweight people – even those who are considered normal weight can be seen with a bit of overhang.
How to prevent opioid addiction before it begins
USC Viterbi School of Engineering researchers are working to combat opioid addiction before it can begin.
Mayo Clinic study finds no evidence that anesthesia in young children lowers intelligence
A Mayo Clinic study finds no evidence that children given anesthesia before their third birthdays have lower IQs than those who did not have it.
Delusions of Creepy Crawlies Plaguing More Than Before?
Delusional infestation — a psychiatric condition formerly known as delusions of parasitosis or Morgellons disease — may be more common than previously thought, a population-based study suggested.
Daytime Drowsiness Could Be Warning Sign Of Alzheimer’s
Excessive sleepiness in the daytime could be an indicator of Alzheimer’s disease, research from the Mayo Clinic indicates.
Minority of inflammatory back pain cases progressed to spondyloarthritis
Patients with new-onset inflammatory back pain have just a 30% chance of developing spondyloarthritis during the next 10 years, and a 43% probability of back pain resolution, according to findings published in Arthritis and Rheumatology.
When the Body Attacks the Brain: Immune System Often to Blame for Encephalitis, Study Finds
Encephalitis caused by the immune system attacking the brain is similar in frequency to encephalitis from infections, Mayo Clinic researchers report in Annals of Neurology.
Obesity increases risk for surgery in patients with ulcerative colitis
Patients with ulcerative colitis who have a higher BMI are at increased risk for bowel resection, according to research presented at the Crohn’s & Colitis Congress.
Improving health globally by studying health locally
Mayo Clinic has been partnering with Olmsted Medical Center and several other regional health care providers for more than 50 years in an initiative called the Rochester Epidemiology Project.
Research finds hysterectomy alone associated with increased long-term health risks
Mayo Clinic researchers show that hysterectomy with ovarian conservation is associated with a significantly increased risk of several cardiovascular diseases and metabolic conditions.